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Zymeworks

NASDAQ: ZYME $24.10 USD~$1B (NASDAQ) MCAP

Zymeworks is a clinical-stage biotechnology company developing multifunctional biotherapeutics for difficult-to-treat cancers. The company's platforms include Azymetric (bispecific antibodies) and EFECT (immune-effector modulation), and it is advancing multiple wholly-owned and partnered oncology candidates. In 2026 Zymeworks expanded its pipeline through the near-$1B acquisition of Theravance Biopharma, adding a lung-disease drug candidate plus royalty streams.

Company Info

Sector:Biotechnology / Oncology Biotherapeutics
Headquarters:Vancouver, British Columbia, Canada
Founded:2003

Upcoming Milestones & Key Dates

Q3 2026
Corporate

Theravance Biopharma acquisition close (~$1B deal announced June 2026)

H2 2026
Clinical Trial

Zanidatamab regulatory and clinical readouts in BTC and GEA

Clinical Development Pipeline

Zanidatamab (ZW25)

Target: Bispecific antibody targeting two HER2 epitopes
HER2-amplified biliary tract cancer; HER2-positive gastroesophageal adenocarcinoma
Preclinical
Phase 1
Phase 2
Phase 3
Approved

Zanidatamab + chemo / ZW49

Target: HER2 bispecific + topoisomerase-based ADC
HER2-positive solid tumors (additional combinations and indications)
Preclinical
Phase 1
Phase 2
Phase 3
Approved

Theravance-originated lung-disease candidate

Target: To be confirmed
Lung disease (specific indication to be confirmed post-acquisition close)
Preclinical
Phase 1
Phase 2
Phase 3
Approved

Recent News

Leadership Team

Kenneth Galbraith

Chair of the Board (interim CEO transition period)

Dr. Sabeen Mekan

Chief Medical Officer

Mark Hollywood

Chief Operating Officer

Careers & Job Openings

See all open roles

Multiple Departments
Vancouver, BC / Remote
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