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Molecular Partners

Molecular Partners AG is a clinical-stage biotechnology company founded in 2004 as a spin-off from the University of Zurich and headquartered in Zurich-Schlieren, Switzerland, with US operations in Concord, Massachusetts. The company pioneered DARPin (Designed Ankyrin Repeat Protein) therapeutics. In October 2026, Molecular Partners announced a strategic pivot to transform into a dedicated targeted radiopharmaceuticals biotech, prioritizing its lead clinical DLL3 Radio-DARPin candidate MP0712 co-developed with Orano Med, while initiating a restructuring cutting up to 44% of headcount (no more than 55 roles).

Company Info

Sector:Radiopharmaceuticals & Oncology (DARPin Therapeutics)
Headquarters:Zurich-Schlieren, Switzerland
Founded:2004

Upcoming Milestones & Key Dates

December 2026
Clinical Data

Initial Phase 1/2a safety data presentation for MP0712 at North America Conference on Lung Cancer

Q2 2027
Corporate Update

Expected completion of workforce restructuring and Swiss consultation process

Clinical Development Pipeline

MP0712 (DLL3 Radio-DARPin)

Target: Delta-Like Ligand 3 (DLL3) / 212Pb Alpha-Emitter (co-developed with Orano Med)
Small Cell Lung Cancer & Neuroendocrine Tumors
Preclinical
Phase 1
Phase 2
Phase 3
Approved

MP0726 (MSLN Radio-DARPin)

Target: Mesothelin (MSLN) / Targeted Alpha Therapy
Mesothelin-Expressing Solid Tumors
Preclinical
Phase 1
Phase 2
Phase 3
Approved

MP0730 (CD70 Radio-DARPin)

Target: CD70 / Targeted Alpha Therapy
Renal Cell Carcinoma & Hematologic Cancers
Preclinical
Phase 1
Phase 2
Phase 3
Approved

Workforce & Restructuring Tracker

View Industry Layoff Tracker →
2026-10-29•Pipeline Pivot & Reprioritization•Zurich-Schlieren, Switzerland
Up to 55 roles (~44%)Confirmed

Clinical-stage biotech Molecular Partners initiated a corporate restructuring to cut up to 55 positions (~44% of workforce) under Swiss labor consultation as it deepens strategic focus into a dedicated radiopharmaceuticals company. Spurred by encouraging Phase 1/2a data for lead DLL3-targeting Radio-DARPin MP0712 (co-developed with Orano Med) in small cell lung cancer, the company is streamlining internal operations to extend its CHF 57.5M ($69M USD) cash runway into late 2027.

Recent News

Leadership Team

Patrick Amstutz, Ph.D.

Chief Executive Officer & Co-Founder

Robert Hendriks

SVP Finance & Executive Management

Anne Goubier, Ph.D.

SVP Biology

Careers & Job Openings

No active job listings. Check back later.