Saram ConsultingGxP & AI Consulting for Life Sciences. Custom AI integrations, Part 11 compliance validation, and equity-based engineering partnerships for biotech.Explore Services at saram.io →
Back to Home

Lexeo Therapeutics

New York City-based clinical-stage genetic medicine company advancing disease-modifying gene therapies for genetic cardiovascular conditions and genetic conditions of the central nervous system; in September 2026 it agreed to acquire Mantle Therapeutics to add Friedreich ataxia assets.

Company Info

Sector:Gene Therapy
Headquarters:New York, New York, USA
Founded:2018

Upcoming Milestones & Key Dates

2026-12
M&A

Close of the Mantle Therapeutics acquisition ($8.3M upfront)

2027
Readout

Further LX2006 and LX2020 clinical data

Clinical Development Pipeline

LX2006

Target: Frataxin (FXN)
Friedreich ataxia cardiomyopathy
Preclinical
Phase 1
Phase 2
Phase 3
Approved

LX2020

Target: PKP2
PKP2-arrhythmogenic cardiomyopathy
Preclinical
Phase 1
Phase 2
Phase 3
Approved

LX3010 (formerly MTL-104)

Target: Oral combination therapy (in-licensed via Mantle acquisition)
Friedreich ataxia
Preclinical
Phase 1
Phase 2
Phase 3
Approved

Recent News

Business & StrategyFierce Biotech

Lexeo acquires Mantle for $8M, adding Friedreich ataxia assets

Lexeo Therapeutics has agreed to acquire Mantle Therapeutics via an upfront payment of $8.3 million, aiming to expand its Friedreich’s ataxia (FA) portfolio while locking in three strategic collabo | Lexeo Therapeutics has agreed to acquire Mantle Therapeutics via an upfront payment of $8.…

Leadership Team

R. Nolan Townsend

Chief Executive Officer

Narinder Bhalla, MD

Chief Medical Officer

Jose Manuel Otero, PhD

Chief Operating Officer

Careers & Job Openings

See all open roles

All departments
Multiple locations
Apply Now