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Curis

NASDAQ: CRIS $4.89 USD~$15M (microcap post-reverse-split, July 2026) MCAP

Curis is a clinical-stage oncology biotechnology company developing emavusertib (CA-4948), an oral IRAK4 inhibitor being studied in combination with ibrutinib in hematologic malignancies (including the TakeAim CLL and TakeAim Lymphoma studies) and as a monotherapy in solid tumors. The company has historically worked on multiple first-in-class targeted cancer therapeutics in partnership with major pharma. Curis completed a 1-for-5 to 1-for-25 reverse stock split effective in July 2026 to maintain Nasdaq listing compliance, with split-adjusted trading beginning shortly thereafter.

Company Info

Sector:Biotechnology / Oncology (Targeted Cancer Therapeutics)
Headquarters:Lexington, Massachusetts, USA
Founded:2000

Upcoming Milestones & Key Dates

Q3 2026
Clinical Trial

Interim TakeAim CLL efficacy and safety update

Clinical Development Pipeline

Emavusertib (CA-4948) + ibrutinib

Target: IRAK4 inhibitor in combination with BTK inhibitor
Relapsed/refractory Chronic Lymphocytic Leukemia (CLL) and primary CNS lymphoma — TakeAim CLL and TakeAim Lymphoma Phase 2 studies
Preclinical
Phase 1
Phase 2
Phase 3
Approved

Emavusertib (CA-4948) monotherapy

Target: IRAK4 inhibitor
Acute Myeloid Leukemia (AML) and high-risk Myelodysplastic Syndromes (MDS)
Preclinical
Phase 1
Phase 2
Phase 3
Approved

Recent News

No recent news updates available for this company.

Leadership Team

James Dentzer

President and Chief Executive Officer

Careers & Job Openings

See all open roles

Multiple Departments
Lexington, MA and remote
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